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lumacaftor/ivacaftor will lessen the extent or result of abemaciclib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Coadministration of abemaciclib with solid CYP3A4 inducers cuts down plasma focus of abemaciclib and its metabolites.For those who have had any liver an infection or been told you've in